SYSTEMIC PLATELET-RICH PLASMA (S-PRP) AS AN ADJUVANT IN THE TREATMENT OF FELINE AZOTEMIA: AN EXPLORATORY CASE SERIES
DOI:
https://doi.org/10.66104/50etnh37Keywords:
felines, systemic therapy, plasma, regenerative therapy, growth factors, integrative medicineAbstract
Feline kidney disease is an important multifactorial disease, frequently associated with tubulointerstitial inflammation, fibrosis, and progressive reduction of renal function. Considering the lack of established regenerative therapies in veterinary medicine, this study aimed to report the use of systemic platelet-rich plasma (S-PRP) as an adjuvant therapy to conventional treatment in three cats with azotemia and clinical alterations compatible with renal dysfunction. Patients underwent fluid therapy and conventional clinical support combined with S-PRP administration. Clinical, laboratory, and ultrasonographic parameters were evaluated before and after the intervention. Clinical improvement was observed, characterized mainly by return of appetite, reduction of nausea, and clinical stabilization, accompanied by a reduction in serum creatinine and urea levels to varying degrees among the evaluated cases. No patient presented adverse effects related to the application of S-PRP during the follow-up period. Despite methodological limitations, the findings suggest potential application of S-PRP as adjuvant therapy in cats with renal dysfunction, reinforcing the need for controlled and standardized studies to evaluate its efficacy and safety.
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