AÇÃO DO LÚPULO EM PACIENTES QUE FAZEM USO DE MEDICAMENTOS PSICOTRÓPICOS
DOI:
https://doi.org/10.61164/rmnm.v6i1.2588Palabras clave:
Hops; interaction; Medicinal Properties; TreatmentResumen
Este estudo explora a interação do lúpulo (Humulus lupulus) com medicamentos psicotrópicos, destacando seus potenciais benefícios terapêuticos e os riscos associados. O lúpulo, conhecido por suas propriedades sedativas e ansiolíticas devido a compostos como alfa-ácidos e 8-prenilnaringenina, pode ser usado para tratar distúrbios de ansiedade e insônia. No entanto, quando combinado com medicamentos psicotrópicos como antidepressivos e ansiolíticos, há o potencial de potencializar os efeitos sedativos, aumentando o risco de sedação excessiva e comprometimento cognitivo. Além disso, o lúpulo pode influenciar a farmacocinética dos medicamentos, alterando sua absorção e metabolismo através do sistema citocromo P450. Este estudo destaca a necessidade de monitoramento clínico rigoroso ao considerar a combinação de lúpulo e medicamentos psicotrópicos, visando maximizar os benefícios terapêuticos enquanto minimiza os riscos para a saúde dos pacientes.
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Referencias
Stahl, S. M. (2013). Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. Cambridge University Press.
• G1. (1 de abril de 2024). Da cerveja à medicina: Entenda como lúpulo pode ser usado contra os vírus chikungunya e oropouche. Recuperado de G1.
• Bhattacharyya, S., Sharma, V. K., & Sharma, A. (2011). Medicinal Properties of Humulus Lupulus L. (Hops): A Review. Indian Journal of Natural Products and Resources, 2(3), 292-299.
• Jones, M. (2020). Herbal Interactions with Psychotropic Medications: A Review. Journal of Clinical Pharmacology, 60(5), 570-580. DOI:10.1002/jcph.1598.
• Stevens JF, Page JE. Xanthohumol and related prenylflavonoids from hops and beer: to your good health! Phytochemistry. 2004;65(10):1317-1330.
• Miranda CL, Stevens JF, Helmrich A, et al. Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines. Food Chem Toxicol. 1999;37(4):271-285. PubMed
• Zanoli P, Zavatti M. Pharmacognostic and pharmacological profile of Humulus lupulus L. J Ethnopharmacol. 2008;116(3):383-396.
• Gerhäuser C. Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites. Mol Nutr Food Res. 2005;49(9):827-831.
• Chadwick LR, Pauli GF, Farnsworth NR. The pharmacognosy of Humulus lupulus L. (hops) with an emphasis on estrogenic properties. Phytomedicine. 2006;13(1-2):119-131.
• Erkkola R, Vervarcke S, Vansteelandt S, Rompotti P, De Keukeleire D. A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts. Phytomedicine. 2010;17(6):389-396.
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