PERFIL TOXICOLÓGICO DE Camellia sinensis: UNA REVISIÓN INTEGRADORA
DOI:
https://doi.org/10.66104/hj0fxz98Palabras clave:
Camellia sinensis, Toxicología, In vitro, In vivoResumen
El uso de plantas medicinales como alternativa terapéutica perdura hace años. En ese sentido, se destaca la Camellia sinensis, cuyo té de sus hojas es la segunda bebida no alcohólica más consumida del mundo asociada a las propiedades terapéuticas. Sin embargo, el consumo exagerado puede causar daños a la salud. Delante de eso, este estudio tuvo como objetivo realizar una revisión integradora respecto de los aspectos tóxicos de la especie. La recolección de datos fue realizada utilizando las bases de datos: BVS, SciELO, Sciencedirect y Pubmed, utilizando los siguientes descriptores en salud (DeCS): Camellia sinensis, toxicology, toxicity, drugs interactions, in vitro, in vivo y adverse reactions, vinculados a los operadores booleanos “AND” y “OR”, como filtro se utilizó el espacio temporal de 2001 a 2025. El levantamiento cuantitativo inicial resultó en 907 artículos de acuerdo con la temática establecida, siendo 145 resultados de la base de datos BVS, 194 en la SciELO, 475 en la Sciencedirect y 93 en la Pubmed, después de los criterios de inclusión y exclusión, fueron incluidos siete artículos para la realización de esta revisión integradora. Se observó que los extractos de Camellia sinensis presentaron, en ensayos in vitro e in vivo, interacciones medicamentosas (antagonismo con quimioterápico), posibles efectos neurotóxicos y hepatotóxicos, además de alteraciones en el metabolismo de folato a dosis altas. Por lo tanto, este estudio evidencia que Camellia sinensis presenta potenciales efectos toxicológicos en condiciones especificas, lo que resalta la importancia de la orientación adecuada y de la continuidad de estudios sobre los riesgos presentados por la especie.
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Derechos de autor 2026 Eduardo Henrique Batista Palheta, Marcelly Christine de Souza Diniz, Cyanne Anastácia Seabra Quaresma, Gyulia Maria Braga Miranda, Eduarda Silveira Merenda, Lucas Quaresma Ferreira, Kevin Lorran da Silva Oliveira, Dr Christian Neri Lameira
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