APLICAÇÕES DE BIOMARCADORES ENZIMÁTICOS EM DOENÇAS CARDIOVASCULARES

Autores

  • André Gomes de Lima FACULDADE UNIDOMBOSCO

DOI:

https://doi.org/10.61164/1k6q2921

Palavras-chave:

Biomarcadores enzimáticos; Doenças cardiovasculares; Troponina; BNP; Diagnóstico precoce; Medicina personalizada.

Resumo

Cardiovascular diseases remain the leading cause of mortality worldwide, demanding increasingly accurate diagnostic strategies. In this context, enzymatic biomarkers have become essential tools in clinical practice, enabling the identification of myocardial injury, risk stratification, and therapeutic monitoring. This article discusses the historical evolution of biomarkers, from classical enzymes such as CK-MB and LDH to modern markers like high-sensitivity troponins and natriuretic peptides (BNP and NT-proBNP). Their clinical applications, technological advances, limitations, and future perspectives are analyzed, emphasizing the role of biomarkers in personalized and preventive medicine.

Downloads

Os dados de download ainda não estão disponíveis.

Referências

DATASUS. Mortalidade por Doenças do Aparelho Circulatório no Brasil. Ministério da Saúde, 2023. Disponível em: http://datasus.saude.gov.br.

Januzzi, J. L.; Mebazaa, A.; Di Somma, S.; et al. Novel Biomarkers in Cardiovascular Disease: Galectin-3, ST2 and Beyond. Circulation Research, v. 134, n. 2, p. 201–215, 2024.

Maisel, A. S.; Daniels, L. B.; Breidthardt, T.; et al. BNP and NT-proBNP in Heart Failure Diagnosis and Management. Journal of the American College of Cardiology (JACC), v. 81, n. 12, p. 1125–1138, 2023.

Mueller, C.; Giannitsis, E.; Christ, M.; et al. Biomarkers in Acute Coronary Syndromes and Heart Failure: Current Evidence and Future Perspectives. Nature Reviews Cardiology, v. 21, p. 123–139, 2024.

McDonagh, T. A.; Metra, M.; Adamo, M.; et al. 2023 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. European Heart Journal, v. 44, n. 4, p. 359–419, 2023.

Thygesen, K.; Alpert, J. S.; Jaffe, A. S.; et al. Fourth Universal Definition of Myocardial Infarction (2023). European Heart Journal, v. 44, n. 3, p. 239–269, 2023.

World Health Organization (WHO). Cardiovascular Diseases Fact Sheet. Geneva: WHO, 2024. Disponível em: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds). Acessado em 04 dez. 2025.

Downloads

Publicado

2025-12-01

Como Citar

APLICAÇÕES DE BIOMARCADORES ENZIMÁTICOS EM DOENÇAS CARDIOVASCULARES. (2025). Revista Multidisciplinar Do Nordeste Mineiro, 21(03), 1-10. https://doi.org/10.61164/1k6q2921