USE OF AUTOGENOUS DENTO-OSSEOUS GRAFT FOR VISION RESTORATION (OSTEO-ODONTO-KERATOPROSTHESIS): A LITERATURE REVIEW

Authors

  • Cindy Meriane Alves de Oliveira Anhanguera College
  • Samir de Moura Gonçalves Leite São Paulo State University
  • Paula Roberta Pires Miranda São Paulo State University
  • Camila da Silva Rodrigues São Paulo State University
  • Natália Rivoli Rossi São Paulo State University
  • Pedro Henrique Condé Oliveira Prado São Paulo State University
  • Milagros Del Valle El Abras Ankha Universidade Estadual Paulista, Brasil
  • Manassés Grangeiro Anhanguera College

DOI:

https://doi.org/10.66104/mvf5mf95

Keywords:

Osteo-odonto-keratoprosthesis, Ocular surgery, Ophthalmologic surgical procedures

Abstract

Osteo-odonto-keratoprosthesis (OOKP) is a surgical technique indicated for visual rehabilitation in patients with blindness caused by severe corneal opacity. It involves the fixation of an autogenous dental element as a biological support for an optical prosthesis, enabling the restoration of visual function. This study aims to review the literature on OOKP, highlighting its technical aspects, clinical indications and contraindications, and the importance of interdisciplinary integration for procedural success. The databases used were PubMed, SciELO, BIREME, and LILACS, from which articles were collected using the following keywords: osteo-odonto-keratoprosthesis, ocular surgery, and ophthalmologic surgical procedures. Osteo-odonto-keratoprosthesis (OOKP) represents a significant advancement in the visual rehabilitation of patients with complex corneal opacity, especially those who are not candidates for conventional corneal transplantation. The selection and preparation of the dental graft, together with the adaptation of dental materials, are crucial steps for achieving positive clinical outcomes and improving patients’ quality of life.

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References

ALEXANDER, J. K. et al. International outcomes of the Boston type I keratoprosthesis in Stevens-Johnson syndrome. Cornea, Philadelphia, v. 34, p. 1387–1394, 2015. DOI: https://doi.org/10.1097/ICO.0000000000000619

AVADHANAM, V. S.; LIU, C. S. C. Keratoprostheses for corneal blindness: a review of contemporary devices. Clinical Ophthalmology, Auckland, v. 9, p. 697–720, 2015. DOI: https://doi.org/10.2147/OPTH.S27083

AVADHANAM, V. S. et al. Clinical study of laminar resorption: Part 1 – factors affecting laminar resorption. The Ocular Surface, Amsterdam, v. 18, n. 4, p. 699–705, 2020. DOI: https://doi.org/10.1016/j.jtos.2020.07.010

BARBER, J. C. Keratoprostheses: past and present. International Ophthalmology Clinics, Boston, v. 28, n. 2, p. 103–109, 1988. DOI: https://doi.org/10.1097/00004397-198802820-00002

BASU, S.; PILLAI, V. S.; SANGWAN, V. S. Mucosal complications of modified osteo-odonto keratoprosthesis in chronic Stevens-Johnson syndrome. American Journal of Ophthalmology, New York, v. 156, n. 5, p. 867–873, 2013. DOI: https://doi.org/10.1016/j.ajo.2013.06.012

CARDONA, H. Mushroom transcorneal keratoprosthesis. American Journal of Ophthalmology, New York, v. 68, n. 4, p. 604–612, 1969. DOI: https://doi.org/10.1016/0002-9394(69)91239-2

CHIRILA, T. V.; HICKS, C. R. The origins of the artificial cornea: Pellier de Quengsy and his contribution to the modern concept of keratoprosthesis. Gesnerus, Basel, v. 56, p. 218–231, 1999.

DE LA PAZ, M. F. et al. Impact of clinical factors on the long-term functional and anatomic outcomes of osteo-odonto-keratoprosthesis and tibial bone keratoprosthesis. American Journal of Ophthalmology, New York, v. 151, n. 5, p. 829–839, 2011. DOI: https://doi.org/10.1016/j.ajo.2010.11.011

DE LA PAZ, M. F. et al. Osteo-odonto-, tibial bone and Boston keratoprosthesis in clinically comparable cases. The Ocular Surface, Amsterdam, v. 17, p. 476–483, 2019. DOI: https://doi.org/10.1016/j.jtos.2019.04.006

DOHLMAN, C. H.; DOANE, M. G. Prosthokeratoplasty. American Journal of Ophthalmology, New York, v. 77, n. 5, p. 694–700, 1974. DOI: https://doi.org/10.1016/0002-9394(74)90534-0

FALCINELLI, G. et al. Modified osteo-odontokeratoprosthesis for treatment of corneal blindness: long-term anatomical and functional outcomes in 181 cases. Archives of Ophthalmology, Chicago, v. 123, n. 10, p. 1319–1329, 2005. DOI: https://doi.org/10.1001/archopht.123.10.1319

HILLE, K. Langzeitverlauf nach Keratoprothesen mit biologischer Haptik. Der Ophthalmologe, v. 115, n. 1, p. 5-11, 2018. DOI: https://doi.org/10.1007/s00347-017-0503-1

HILLE, K. et al. Standards for modified osteo-odonto-keratoprosthesis (OOKP) surgery according to Strampelli and Falcinelli: the Rome-Vienna protocol. Cornea, Philadelphia, v. 24, n. 8, p. 895–908, 2005. DOI: https://doi.org/10.1097/01.ico.0000157401.81408.62

IYER, G. et al. Modified osteo-odonto keratoprosthesis—the Indian experience: results of the first 50 cases. Cornea, Philadelphia, v. 29, n. 7, p. 771–776, 2010. DOI: https://doi.org/10.1097/ICO.0b013e3181ca31fc

IYER, G. et al. Laminar resorption in modified osteo-odonto-keratoprosthesis procedure: a cause for concern. American Journal of Ophthalmology, New York, v. 158, n. 2, p. 263–269, 2014. DOI: https://doi.org/10.1016/j.ajo.2014.03.004

IYER, G. et al. Keratoprosthesis: current global scenario and a broad Indian perspective. Indian Journal of Ophthalmology, Mumbai, v. 66, n. 5, p. 620–629, 2018. DOI: https://doi.org/10.4103/ijo.IJO_22_18

LEE, W. B. et al. Boston keratoprosthesis: outcomes and complications. Ophthalmology, San Francisco, v. 122, n. 7, p. 1504–1511, 2015. DOI: https://doi.org/10.1016/j.ophtha.2015.03.025

LIU, C. et al. Visual rehabilitation in end-stage inflammatory ocular surface disease with the osteo-odontokeratoprosthesis. British Journal of Ophthalmology, London, v. 92, n. 9, p. 1211–1217, 2008. DOI: https://doi.org/10.1136/bjo.2007.130567

MICHAEL, R. et al. Long-term functional and anatomical results of osteo- and osteoodontokeratoprosthesis. Graefe’s Archive for Clinical and Experimental Ophthalmology, Berlin, v. 246, p. 1133–1137, 2008. DOI: https://doi.org/10.1007/s00417-008-0850-3

ORTIZ-MORALES, G. et al. The evolution of the modified osteo-odonto-keratoprosthesis, its reliability, and long-term visual rehabilitation prognosis: an analytical review. Survey of Ophthalmology, New York, 2022. DOI: https://doi.org/10.1016/j.jtos.2022.03.005

RISHI, P. et al. Vitreoretinal complications and outcomes in eyes undergoing surgery for modified osteo-odonto-keratoprosthesis. Ophthalmology, San Francisco, v. 125, n. 6, p. 832–841, 2018. DOI: https://doi.org/10.1016/j.ophtha.2017.12.003

SAWATARI, Y. et al. Oral and maxillofacial surgeons’ role in the first successful modified osteo-odontokeratoprosthesis performed in the United States. Journal of Oral and Maxillofacial Surgery, Philadelphia, v. 69, n. 6, p. 1750–1756, 2011. DOI: https://doi.org/10.1016/j.joms.2010.07.055

STRAMPELLI, B. Osteo-odontokeratoprosthesis. Annali di Ottalmologia e Clinica Oculistica, v. 89, p. 1039–1044, 1963.

TAN, A.; TAN, D. T. H.; MEHTA, J. S. Osteo-odonto keratoprosthesis: systematic review of surgical outcomes and complication rates. The Ocular Surface, Amsterdam, v. 10, n. 1, p. 15–25, 2012. DOI: https://doi.org/10.1016/j.jtos.2012.01.003

TAY, A. B. G. et al. Osteo-odonto-keratoprosthesis surgery: a combined ocular–oral procedure for ocular blindness. International Journal of Oral and Maxillofacial Surgery, Copenhagen, v. 36, n. 9, p. 807–813, 2007. DOI: https://doi.org/10.1016/j.ijom.2007.04.009

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Published

2026-04-15

Issue

Vol. 13 No. 06 (2026): REMUNOM - ISSN 2178-6925

Section

Artigos

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Copyright (c) 2026 Cindy Meriane Alves de Oliveira, Samir de Moura Gonçalves Leite, Paula Roberta Pires Miranda, Camila da Silva Rodrigues, Natália Rivoli Rossi, Pedro Henrique Condé Oliveira Prado, Milagros Del Valle El Abras Ankha, Manassés Tercio Vieira Grangeiro

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How to Cite

USE OF AUTOGENOUS DENTO-OSSEOUS GRAFT FOR VISION RESTORATION (OSTEO-ODONTO-KERATOPROSTHESIS): A LITERATURE REVIEW. (2026). REMUNOM, 13(06), 1-13. https://doi.org/10.66104/mvf5mf95