USE OF CNAF IN THE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE-COPD. AN INTEGRATIVE LITERATURE REVIEW
DOI:
https://doi.org/10.66104/tv919k44Keywords:
CNAF, Chronic Obstructive Pulmonary Disease, CNAF and exacerbated COPD, Urgency and Emergency.Abstract
Objective: To identify the benefits, effectiveness, and limitations of using positive pressure via high-pressure nasal cannula (HFNC) in patients admitted to the hospital emergency department during COPD exacerbations. Methodology: This is an integrative literature review. The sample consisted of people with COPD in exacerbation who benefit from or do not benefit from HFNC. This research was conducted using the SciELO, PEDro, BVS, and PubMed databases. Articles published in journals, complete, from 2020 to 2025 were included. Results: HFNC is more comfortable and tolerable than non-invasive ventilation (NIV), reduces muscle work, reduces areas of alveolar collapse, enabling normal oxygen saturation, preventing acute pulmonary edema, and reducing intubation and mortality rates. Conclusion: It is concluded from this evidence that HFNC, like NIV, has its peculiarities. However, when evaluating their effects during COPD exacerbation, in cases of acute renal failure, post-intubation cases, and others, there are not enough findings to ensure that the use of one of these therapies is superior to another, especially in cases of exacerbated COPD.
Downloads
References
World Health Organization (WHO) [homepage on the Internet]. Geneva: WHO; c2022 [updated 2021 Jun 21; cited 2022 Mar 11]. Chronic Obstructive Pulmonary Disease (COPD); [about 8 screens]. Available from: https://www.who.int/news-room/fact-sheets/detail/ chronic-obstructive-pulmonary-disease-(copd)
Oltra G, Ricciardelli M, Virgilio S, Fernandez Parmo D, Ruiz A, Liquitay CME, Garegnani L Physiotherapy Research International 2024 Apr;29(2):e2088 systematic review
Interventions to improve rates of successful extubation in preterm infants: a systematic review and meta-analysis [with consumer summary] Ferguson KN, Roberts CT, Manley BJ, Davis PG JAMA Pediatrics 2017 Feb;171(2):165-174 systematic review
Nasal continuous positive airway pressure immediately after extubation for preventing morbidity in preterm infants. Ho JJ, Kidman AM, Chua B, Chang G, Fiander M, Davis PG. Cochrane Database Syst Rev. 2024 Oct 11;10(10):CD000143. doi: 10.1002/14651858.CD000143.pub2. PMID: 39392114
Physiother Res Int . 2024 Apr;29(2):e2088. doi: 10.1002/pri.2088.
High-flow nasal cannula during pulmonary rehabilitation for people with chronic obstructive pulmonary disease: A systematic review and meta-analysis Gisela Oltra 1, Mariela Ricciardelli 2, Sacha Virgilio 2, Delfina Fernandez Parmo 2, Angélica Ruiz 2, Camila Micaela Escobar Liquitay 1, Luis Garegnani 1 Affiliations Expand PMID: 38581398 DOI: 10.1002/pri.2088
Inteligência de Ressegurança Biomédica . 2020 Out 2:2020:7097243. doi: 10.1155/2020/7097243. eCollection 2020. Eficiência da Cânula Nasal de Alto Fluxo na Reabilitação Pulmonar em Pacientes com DPOC: Uma Meta-Análise Cupping Fu 1, Xin Liu 2, Qingqing Zhu 1, Xu Wu 3, Shengyu Hao 3, Liang Xie 3, Shanqun Li 3 Afiliações Expandir PMID: 33083481 PMCID: PMC7556103 DOI: 10.1155/2020/7097243
Comparison of high flow nasal cannula with noninvasive ventilation in chronic obstructive pulmonary disease patients with hypercapnia in preventing postextubation respiratory failure: a pilot randomized controlled trial Jing G, Li J, Hao D, Wang T, Sun Y, Tian H, Fu Z, Zhang Y, Wang X Research in Nursing & Health 2019 Jun;42(3):217-225 clinical trial
Celli BR, Fabbri LM, Aaron SD, et al. Diagnóstico diferencial de suspeitas de exacerbações da doença pulmonar obstrutiva crônica no ambiente de cuidados agudos: melhores práticas. Am J Respir Crit Care Med. 2023; 207(9):1134–1144. doi: 10.1164/rccm.202209-1795CI
Marcos PJ, Sanjuán P, Huerta A, et al. Relação entre a classificação de gravidade da exacerbação aguda da doença pulmonar obstrutiva crônica e os desfechos clínicos em pacientes hospitalizados. Cureu. 2017; 9(1):e988. doi: 10.7759/cureus.988
Berenyi F, Steinfort DP, Abdelhamid YA, et al. Características e Desfechos de Pacientes Criticamente Doentes com Exacerbação Aguda de Doença Pulmonar Obstrutiva Crônica na Austrália e Nova Zelândia. Ann Am Sociedade Torácica. 2020; 17(6):736–745. doi: 10.1513/AnnalsATS.201911-821OC
Contemporary Concise Review 2022: Doença pulmonar obstrutiva crônica Peter M. A. Calverley, Paul P. Walker Primeira publicação: 15 de março de 2023 https://doi.org/10.1111/resp.14489
Nagata K, Horie T, Chohnabayashi N, Jinta T, Tsugitomi R, Shiraki A, et al. Home high-flow nasal cannula oxygen therapy for stable hypercapnic COPD: a randomized clinical trial. Am J Respir Crit Care Med. 2022;206(11):1326–35
Nagata K, Horie T, Chohnabayashi N, Jinta T, TsSpoletini G, Cortegiani A, Gregoretti C. Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: a narra tive review. Trends Anaesth Crit Care. 2019;26–27:22–9.ugitomi R, Shiraki A, et al. Home high-flow nasal cannula oxygen therapy for stable hypercapnic COPD: a randomized clinical trial. Am J Respir Crit Care Med. 2022;206(11):1326–35
10 de dezembro de 2024; 333(10):875–890. doi: 10.1001/jama.2024.26244
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Anderson Rodolfo da Silva Oliveira , Cristina Ingrid Aguiar Cardozo, Francisca Tamiris Pereira de Souza, Helenicy Nogueira Holanda Veras, Ivo Saturno Bonfin, Monica de Sousa Oliveira, Nádia de Melo Alves Portela, Noêmia Maria Sousa Oliveira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in this journal agree to the following terms:
Authors retain copyright and grant the journal the right of first publication, with the work simultaneously licensed under the Creative Commons Attribution License, which permits the sharing of the work with proper acknowledgment of authorship and initial publication in this journal;
Authors are authorized to enter into separate, additional agreements for the non-exclusive distribution of the version of the work published in this journal (e.g., posting in an institutional repository or publishing it as a book chapter), provided that authorship and initial publication in this journal are properly acknowledged, and that the work is adapted to the template of the respective repository;
Authors are permitted and encouraged to post and distribute their work online (e.g., in institutional repositories or on their personal websites) at any point before or during the editorial process, as this may lead to productive exchanges and increase the impact and citation of the published work (see The Effect of Open Access);
Authors are responsible for correctly providing their personal information, including name, keywords, abstracts, and other relevant data, thereby defining how they wish to be cited. The journal’s editorial board is not responsible for any errors or inconsistencies in these records.
PRIVACY POLICY
The names and email addresses provided to this journal will be used exclusively for the purposes of this publication and will not be made available for any other purpose or to third parties.
Note: All content of the work is the sole responsibility of the author and the advisor.
